…on Monday, is here to make some comments on Dr. Hoffer's paper. Without further ado, Dr. Bennett. Thank you. Thank you very much, Mr. Chairman, and friends. Dave Hoffer and I have known each other now since 1955. I recall the first evening that we had together. It was in a hotel room in Atlantic City. We found that we were treading mutual pathways. I'm also an experimental psychiatrist, so to speak. Unfortunately, I don't have the chemical background that Abe has, which you can see has stood him in such excellent esteem during this talk. At that meeting, Abe was there with Roland Fisher and with Herb Sprintz and myself. Herb is an international authority on metabolism. You know very well of Dr. Hoffer's work. And Roland Fisher now is doing some exciting work on thyroid metabolism, taste acuity, and hallucinogenic drugs in Ohio. So it's a great deal of pleasure that I accept this invitation to comment on Dr. Hoffer's work. There are several things that are merely outstanding. One is that Dr. Hoffer has done a tremendously effective job in a cohesive presentation of a most difficult field. He summarized for us over ten years of direct personal research efforts in this whole aspect of schizophrenia, alcoholism, nicotinic gas metabolism. There are only a few things that I can add to this. First, I must admit that I have not used a high dose of nicotinic acid myself, but I've always been sympathetic with Dr. Hoffer's work. I consider him as one of the leading advocates in terms of being a brain factory in one person. His contributions to the field of experimental psychiatry have been enormous, with many, many publications giving us many, many exciting leads and directions to follow. However, in the literature we find that nicotinic acid was used first by Dr. Hoffer's group in about 55 in the treatment of hypercholesterolemia. And following this exciting study, it was used by other individuals, particularly internists at the Mayo Clinic, for the relief of this condition. I want to cite some literature on its use because in this literature we can glimpse some possible toxicological effects of continuous high dose nicotinic acid. Dr. Hoffer mentioned that in his own personal experience, this has not been serious. But I do want to go with you over literature to see what may result. Dr. Berge, B-R-G-E, Mayo…